Differential regulation of glutamate receptors in trigeminal ganglia following masseter inflammation
نویسندگان
چکیده
منابع مشابه
Transcriptome analysis of trigeminal ganglia following masseter muscle inflammation in rats
BACKGROUND Chronic pain in masticatory muscles is a major medical problem. Although mechanisms underlying persistent pain in masticatory muscles are not fully understood, sensitization of nociceptive primary afferents following muscle inflammation or injury contributes to muscle hyperalgesia. It is well known that craniofacial muscle injury or inflammation induces regulation of multiple genes i...
متن کاملNeuronal plasticity of trigeminal ganglia in mice following nerve injury
BACKGROUND Nerve injury may induce neuropathic pain. In studying the mechanisms of orofacial neuropathic pain, attention has been paid to the plastic changes that occur in the trigeminal ganglia (TGs) and nucleus in response to an injury of the trigeminal nerve branches. Previous studies have explored the impact of sciatic nerve injury on dorsal root ganglia (DRGs) and it has shown dramatic cha...
متن کاملRegulation of intrinsic and synaptic properties of neonatal rat trigeminal motoneurons by metabotropic glutamate receptors.
We studied how metabotropic glutamate receptor (mGluR) activation modifies the synaptic and intrinsic membrane properties of neonatal rat trigeminal motoneurons using the broad-spectrum mGluR agonist (1S,3R)-1-amino-1,3-cyclopentane-dicarboxylic acid [(1S,3R)-ACPD], group I/II antagonist (+/-)-alpha-methyl-4-carboxy-phenylglycine (MCPG), and group III agonist L-2-amino-4-phosphonobutanoate (L-A...
متن کاملTrigeminal schwannoma presenting as atypical trigeminal neuralgia and masseter atrophy.
A 58-year-old man presented with progressive paresthesia and constant pain at left temporal and anterior auricular area for four months, who characterized the pain as sharp and lancinating in moderate to severe degree, with radiation to lower face, and aggravated while chewing. Two months later, he noticed progressive buccal muscle wasting. Neurologic examination (NE) showed sensory impairment ...
متن کاملBrain-derived neurotrophic factor enhances the excitability of small-diameter trigeminal ganglion neurons projecting to the trigeminal nucleus interpolaris/caudalis transition zone following masseter muscle inflammation
BACKGROUND The trigeminal subnuclei interpolaris/caudalis transition zones (Vi/Vc) play an important role in orofacial deep pain, however, the role of primary afferent projections to the Vi/Vc remains to be determined. This study investigated the functional significance of hyperalgesia to the brain-derived neurotrophic factor (BDNF)-tyrosine kinase B (trkB) signaling system in trigeminal gangli...
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ژورنال
عنوان ژورنال: Neuroscience Letters
سال: 2007
ISSN: 0304-3940
DOI: 10.1016/j.neulet.2007.05.031